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Load vs Reps: What the 2024-2025 Research Says About Progressive Overload

2026-02-14

Building muscle and strength isn't complicated, but programming progression is where most lifters get stuck. Should you chase heavier weights or more repetitions? A wave of recent research from 2024-2025 has new answers — and they're more nuanced than the old "just add weight" dogma.

The Traditional Wisdom (and Its Flaws)

For decades, progressive overload has been drilled into every lifter's brain: add weight when you can. The problem? This assumes your body adapts linearly, ignoring daily fluctuations in sleep, stress, recovery, and fatigue.

A 2024 randomized controlled trial put this to the test in a clever way. Researchers had 39 untrained adults (20 men, 19 women) train one leg by adding weight each week, while the other leg added repetitions — holding total volume constant. After 10 weeks of leg extension training, both groups saw nearly identical gains:

  • Load progression group: 1RM went from 52.9 kg to 69.1 kg; muscle cross-sectional area increased from 21.3 cm² to 23.5 cm²
  • Rep progression group: 1RM went from 51.7 kg to 66.8 kg; muscle cross-sectional area increased from 21.1 cm² to 23.4 cm²
The difference? Statistically insignificant. Both approaches worked equally well for early-stage lifters [Scarpelli et al., 2024](https://pubmed.ncbi.nlm.nih.gov/38286426/).

This challenges the idea that heavier is always better. But before you ditch the barbell, there's more nuance.

The Real Key: Autoregulation

Where things get interesting is in the 2025 research on autoregulated training methods. A network meta-analysis published in 2025 compared four approaches for maximal strength:

  • Percentage-Based Resistance Training (PBRT) — Traditional % of 1RM
  • RPE-Based Training — Rating of Perceived Exertion / Reps in Reserve
  • Velocity-Based Training (VBRT) — Tracking bar speed
  • Autoregulating Progressive Resistance Exercise (APRE) — Self-adjusting protocols
The results? For back squat, APRE ranked highest (93% probability of being best), followed by RPE (67%), VBRT (27%), and traditional %-based training (13%). Similar patterns held for bench press [PMC, 2025](https://pmc.ncbi.nlm.nih.gov/articles/PMC12336695/).

The common thread: methods that account for daily readiness outperformed rigid percentage-based programming.

Why Autoregulation Wins

Traditional %1RM programming has a fatal flaw — it assumes you're equally ready to train every day. You're not. Sleep debt, life stress, accumulated fatigue, and minor injuries all fluctuate. What felt like 80% last week might be 85% today.

RPE and RIR (Reps In Reserve) solve this elegantly. Instead of "3 sets of 5 at 80%," you do "3 sets of 5 at RPE 7-8" (meaning 2-3 reps left in the tank). On good days, you might get 6-7 reps. On bad days, you might hit 4-5. You're still training hard — just appropriately scaled to your capacity that day. Velocity-based training takes a different approach: lighter loads moved faster generally produce similar strength gains to heavier loads moved slower, but with less fatigue accumulation. If your bar speed drops below a certain threshold, you stop — preventing the "grinding" that leads to injury.

Practical Takeaways

Based on the current science, here's what actually works:

For Beginners (First 6-12 Months)

Either load or rep progression will get you results. Pick whichever feels more sustainable. The 2024 study shows both work nearly identically.

For Intermediate-Advanced Lifters

Autoregulation matters more as you advance. Your linear progression days are numbered. Consider:
  • RPE-based programming: "3x5 @ RPE 7-8" or "5x5 @ RPE 8"
  • Double progression: Work within a rep range (e.g., 8-12), add reps until you hit the top end, then increase weight

For Everyone

  • Don't grind to failure every session — it accumulates fatigue faster than gains
  • Track something: reps, RPE, or velocity. Data beats intuition.
  • Listen to your body: If 80% feels like 90% today, it probably is

The Bottom Line

The "just add weight" approach isn't wrong — it's just incomplete. The 2024-2025 research confirms that progressive overload can happen through weight OR reps, but the real competitive advantage is autoregulation: matching your training demand to your daily capacity.

Stop chasing arbitrary numbers. Start training smarter.


References:
  • Scarpelli et al. (2024). Effects of Resistance Training Overload Progression Protocols on Strength and Muscle Mass. International Journal of Sports Medicine. PMID: 38286426
  • Network Meta-Analysis (2025). Autoregulated resistance training for maximal strength enhancement. ScienceDirect. PMC: PMC12336695

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